Tag Archives: neuris

Rant

Anxiety Medication Fail (Yet Again)

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One thing that you should know about me is that I don’t seem to be able to learn a lesson. I am writing this just a few weeks after my latest anxiety medication fail.

So, I had a good thing going on with my medications, no problems, good productivity, happy in life. But, I started looking for ways to cheap out. I found a pharmacy which would provide me cheaper versions of the medications I currently take from my hospital.

MedicationBeforeAfter
Escitalopram 10mg (Half Dose)LexaproEsidep
Risperidone 1mg (Half Dose)NeurisRisperidone GPO
Before and after medication

Basically I replaced my expensive medication with cheaper versions, with supposedly the exact same chemical composition, but at 1/4th the price. What could go wrong?

Lots.

Turns out, all medication are not created equal, even if the box says so.

The first night I switched meds, I had awful sleep and woke up the next morning with an altered mental state. I had a work-related argument the night before, so I thought it was related to that.

The second night, too, I slept awful. At this point, I started suspecting the meds, but decided to give it another try.

Luckily, I still had some of my old medication left. So I decided to do a series of experiments

  1. Third night I rolled back Escitalopram to Lexapro – No Joy
  2. Fourth night I rolled back both medications – Much joy
  3. Fifth & Sixth night, I did Esidep + Neuris – Much joy

Hence, I identified that the Risperidone generic version is no good. The next day, I went to the doctor and got my regular medication.

Anxiety Medication Withdrawal Fail
The Culprit
Health & Fitness

Anxiety Medication Withdrawal Fail-3

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Continuing my series about my battle with anxiety, this is a new year special. My latest medication withdrawal fail and third in a year.

So I planned a vacation to Hua Hin for new years. I am anyways not completely at ease while travelling, but this time I topped it by forgetting to take my medication with me. Epic fail! when I realized this, I considered scouring the local pharmacies, begging for prescription medication like a junkie. But since it was only 2 days, I decided to swallow the pill.

Night 1/Day 1

I had a decent amount of alcohol to numb me down and delayed my sleep as much as possible. Once I was really sleepy, I went to sleep. Luckily I fell asleep relatively easy. However, I woke up after a few hours drenched in sweat with my heart trying to escape my chest. I tried going back to sleep but the rest of the night I was in an out of sleep. While being acutely aware of my heartbeat.

Woke up the next day tired. The day was better than the night but was jittery throughout. Sometime during late morning, my hands started shaking. After having some Coca Cola and chilling at the beach, I felt much better. By evening I was almost normal.

At night we went to a New Years Eve party on the beach and I consumed alcohol to distract myself from the impending time I have to go to sleep.

Night 2/Day 2

I went to sleep at 11. Luckily, I fell asleep without much issues, but the fireworks at midnight woke me up. I spent the first few hours of 2023 tossing and turning in bed. I was tired and I was sleepy. But I just couldn’t fall asleep. It was like a brick wall. Eventually I fell asleep but most of the night I was in and out of sleep.

Next morning I woke up tired but otherwise OK. Drove back home and went for a run to clear my head as soon as I came back. Feet felt like bricks while running. Resisted the temptation to pounce on my medication immediately.

In the evening, I figured that I am likely already past the worst phase of the withdrawal so why even go back on my earlier full dose? I had half a dose (0.5mg, compared to 1mg original dose) and went to sleep very tired.

Sleep Changes

One thing I noticed is that my sleep had turned very light, especially in the second half of the night. I was able to fall asleep and sleep well for the first few hours, but for the second half, I was in a strange state. It felt as if I am awake, but I am not because time passes too fast. But I have awareness of things around me, daylight etc. I was miserable, but decided to stick to it to avoid another medication withdrawal fail.

Nights 3/4/5

Nights 3/4/5 went equally poorly. I could only sleep for the first few hours each night and woke up mid-way and failed to go back to proper sleep again.

The days also started seeming gloomier and sadder in general. I even gave up alcohol temporarily.

On day 6, I decided to chalk this up as a medication withdrawal fail and upped my dose to 0.75mg, which is still lower than 1mg, my original dose. With 0.75mg, I am doing more or less okay, something I can live with.

Overall, not a complete withdrawal fail, as I was able to reduce my dosage, by a bit. Baby steps, baby steps.

Health & Fitness, Rant

The Serotonin Misadventure

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Recently, I had a misadventure with my serotonin levels. As I posted earlier, I have been on Neuris 1mg- An Antipsychotic & Lexapro 5mg- An SSRI for my Generalized Anxiety Disorder since I moved to Thailand.

Now, the Lexapro, in Thailand costs 15 times what it cost in India. Always one trying to cheap out, on my last doctor’s visit, I asked him if he could prescribe me a cheaper alternative. He prescribed me Fluoxetine 20mg instead and I happily went on my way chalking this up as a win.

After a few days, I started noticing signs of heart palpitations and sweats through the day. I had recently joined a gym so I chalked this up to the workouts. However, the palpitations became worse with time.

It was not until my family left for vacation leaving me alone with my dog at home that the symptoms hit hard.

I was in a state of constant anxiety. My heart felt it was going to burst out of my chest. To make matters worse, I took a Lexapro, too. It really pushed me over the edge and after suffering all day from a constant state of agitation I dumped my dog with the neighbours and went to the ER.

Serotonin Misadventure
Saw many such alerts throughout the day

They said I have Serotonin Syndrome, from an overdose of SSRIs. They shot me up with a sedative and sent me home with a few pills of Ativan. Ah! Bliss!

I slept for 11 hours and woke up the next day feeling much better. Things didn’t go back to normal immediately, but I could feel the improvements over the next few days; all I had to do was not take the SSRIs.

Lesson Learnt : Don’t mess with medication that work, just to cheap out.

PS: On SSRIs, I used to have vivid movie-like dreams. After stopping the SSRIs, the dreams stopped, too.

Health & Fitness, Rant

Anxiety Medication Withdrawal Fail

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As discussed before, I have been on medication to treat my GAD for the past few years. I was lucky to have found a doctor who prescribed me medication instead of sending me to therapy. The medication had been working beautifully, but I always assumed that I won’t take them forever. When I moved to Bangkok, I decided to quit, as I won’t find a doctor here to continue the prescription. I put it off for many months fearing medication withdrawal. Running low on supplies, few weeks ago, I decided that that time was here.

I had been on the following medication to treat my GAD

Medication withdrawal

With high optimism and hope in my heart, I started the process of quitting, one medication at a time.

Levowave

Getting off Levowave was relatively easy. First I halved my dose for a week and then changed it to 3 days a week, then stopped completely. I had some confusion, irritability, anxiety, tremors for a couple of days but after that I was back to normal. No impact on sleep at all.

I assumed that the withdrawal for the other medications would be as easy. How wrong I was!

Buspin

I assumed this one would be the easiest to stop, but I was dead wrong. I halved the dose and in just 2 days, shit hit the fan.

  • Night 1/Day 2 – Uneventful
  • Night 2 – On night 2, suddenly I woke up at 01:00 AM with my heart beating fast, for no apparent reason. I was up for an hour, but was able to go back to (restless) sleep afterwards.
  • Day 2 – The entire day I was full of anxiety, irritable and confused. Lost my appetite. There was also a phase where I had to abuse random strangers on twitter for no reason.
  • Night 3 – Night 3 was horrible. I slept at 21:30 but woke up at 23:00. After that whatever I tried, I couldn’t go back to sleep. I either felt too hot (sweating) or too cold (shivering). After tossing and turning for hours and rousing the rest of my family, I think I finally managed to fall asleep at 04:00. Libido was also up 10x. Heart rate was above 90 bpm throughout.
  • Day 3 – Day 3 started slightly better than Day 2. I started running again, which brought back my appetite. But later in the day, my heart rate rose above 100bps doing nothing. A sense of doom & gloom pervaded my brain and I had only negative thoughts.

I Quit

Sometime in the afternoon of Day 3, I realised that I cannot go through with this and decided to go back on my remaining pills. I booked a doctor’s appointment to get a prescription to resume the medication.

Day 4 – I woke up refreshed after 10 hours of beautiful sleep. The world seemed brighter, and life seemed more beautiful.

After resuming my medication, I finally saw a doctor here. Fortunately, he was kind and patient and prescribed me medication to continue. Unfortunately, not all my medication is available in Thailand, so I have to switch medication.

After all this, I am extremely grateful for my medicines and medical science in general. I will never again take them for granted.